Oxidative stress: The silent accelerator of skin aging

Oxidative stress is considered one of the most significant contributors to premature skin aging. Free radicals — triggered by UV radiation, environmental pollution, and chronic stress, among other things — can damage collagen, elastin, and skin cells. But how can oxidative stress actually be measured, and which measures demonstrably protect the skin?

In an interview, dermatologists Dr. Anette Zimpfer-Keese and Dr. Christine Zimpfer explain the role antioxidants play, who can benefit from having their antioxidant status measured, and why prevention extends far beyond good skincare.

What oxidative stress triggers in the skin

Many people have heard the term "oxidative stress" – but what does it actually mean?

Dr. Anette Zimpfer-Keese: Oxidative stress occurs when the body produces increasing amounts of so-called free radicals — aggressive oxygen molecules that can damage our cells. Up to a certain point, this is a completely normal process, as the body is generally able to neutralize and break down free radicals on its own.

Problems arise when too many free radicals are produced or the body's natural defenses are overwhelmed. Triggers can include external factors such as UV radiation from the sun, alcohol, smoking, or environmental toxins. But also lack of sleep, chronic stress, lack of exercise, hormonal changes, chronic inflammation, certain medications, or metabolic diseases can contribute to oxidative stress.

In the skin, free radicals attack important structures such as collagen, elastin, and even the skin cells themselves. As a result, the skin loses its firmness and elasticity more quickly, ages prematurely, and becomes more sensitive