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August 28, 2025
Hanja Niederhammer
Mesobotox combines the effects of botulinum toxin with stimulating mesotherapy into an effective anti-aging method.
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No more frozen facial expressions, but please no more visible wrinkles either? It is precisely in this balance that the strength of mesobotox lies. The method is considered finer, more dosed, and more natural than classic botox, and is especially popular with those who want freshness without rigidity. But what exactly is mesobotox and who is the treatment worthwhile for?
Mesobotox (also known as microtox or mesotox) is a modern anti-aging method in which highly diluted botulinum toxin is specifically introduced into the superficial layers of the skin. Unlike the classic botox treatment, mesobotox does not aim for muscle paralysis, but for the visible improvement of the skin structure: fine lines are smoothed, pores appear smaller, the complexion looks more even - without changing the natural facial expression.
A diluted variant of the well-known botulinum toxin is used - sometimes combined with hyaluronic acid or vitamin cocktails. The botulinum toxin ensures that fine muscle fibers relax, while additional active ingredients further revitalize the skin.
While classic botox is injected selectively into deeper muscle areas, the application of mesobotox is surface-wide and close to the skin surface. The method targets the finest muscle parts and sebaceous glands, leading to a particularly subtle, natural result.
For which goals is which method suitable?
The treatment is ideal for people in their mid-30s who want to smooth out first wrinkles or refine large-pored skin without looking artificial. Pregnant or breastfeeding women, as well as people with muscle diseases or allergies to botulinum toxin, should avoid it.
Especially for sensitive or thin skin, MesoBotox is often better tolerated than conventional Botox. The microinjections irritate the skin less deeply and provide an even, subtle smoothing.
Advantages of Mesobotox at a glance
Natural look without stiff facial expressions
Typical zones are:
Mesobotox can also be used specifically for hyperhidrosis (excessive sweat production), such as under the armpits, on the forehead, or on the hands. The finely dosed injection of highly diluted botulinum toxin effectively inhibits the activity of the sweat glands.
Before the treatment, a detailed medical history is taken to clarify skin type, target areas, and individual expectations. Allergies or pre-existing conditions are taken into account.
The active ingredient solution is distributed under the skin with the finest needles - punctually, but without deep punctures. The treatment takes about 20–30 minutes.
Refraining from sports, sauna, and makeup for 24 hours is recommended. Light redness or swelling usually subsides on the same day.
This is what a Mesobotox treatment looks like:
First effects appear after 3 to 5 days: the skin looks more relaxed and fresher. The full effect unfolds within 1 to 2 weeks.
On average every 3 to 4 months. For some patients, one application per half year is sufficient.
Depending on skin type and metabolism, about 3 to 4 months. With regular use, the effect often lasts longer.
Those who search online for "mesobotox before and after" often come across impressive comparisons: finer pores, smoothed forehead lines, an even complexion. However, the effect is gentle. No facial changes, just a refreshed, rested look.
Mild swelling, small hematomas, or a feeling of tension are possible but usually subside after a few hours. Serious side effects are rare, but improper application can lead to muscle asymmetries.
The Mesobotox costs range between 250 and 450 euros per treatment, depending on the region and doctor.
People with rosacea often wonder: Mesobotox and rosacea - are they compatible? Good news: The microfine application is usually more suitable than classic Botox therapies. However, each application should be individually examined and closely medically supervised.
Meso-botox can be ideally combined with moisturizing and regenerative treatments:
A harmonious combination concept ensures the natural glow - without the overdone effect.
